Charlotte vs Greenville: Medical Assistant Salary (2026)
Compare medical assistant salaries between Charlotte, NC and Greenville, NC. All figures are 2026 estimates projected from BLS 2025 data.
Side-by-Side Comparison
| Metric | Charlotte, NC | Greenville, NC |
|---|---|---|
| Median Salary | $48,832▲ | $46,869 |
| Hourly Rate | $23.47▲ | $22.54 |
| Entry Level (P10) | $38,440▲ | $36,068 |
| 25th Percentile | $41,778▲ | $39,868 |
| 75th Percentile | $51,446▲ | $48,853 |
| Top Earner (P90) | $59,665▲ | $48,853 |
| Total Employed | 6,060▲ | 600 |
Verdict
Charlotte, NC offers better overall compensation for medical assistants, winning 4 out of 4 metrics compared to Greenville.
The salary gap between Charlotte and Greenville is $1,963 (4.19%). Charlotte's median is +1.82% compared to the US national median of $47,961.
Salary Range Comparison
The full salary range (10th to 90th percentile) in Charlotte spans $21,225,Greenville spans $12,785. Charlotte has a wider pay range, meaning more potential for high earners but also more variation.
Cost-of-Living Adjusted Comparison
After cost-of-living adjustment, Greenville ($53,018 effective) pays 5.69% more than Charlotte ($50,162 effective).
Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.
Which City Is Right for You?
Choose Charlotte if…
- ✓Higher median salary ($48,832/year)
- ✓Better top-earner potential ($59,665)
- ✓Larger job market (6,060 employed)
- ✓You prefer the North Carolina area and lifestyle
Choose Greenville if…
- ✓Better purchasing power (CoL-adjusted: $53,018)
- ✓You prefer the North Carolina area and lifestyle
Historical Salary Growth Comparison
Based on BLS OEWS metropolitan area data, medical assistant salaries in Charlotte grew 34.6% from 2019 to 2025, compared to 45.3% growth in Greenville over the same period.
Charlotte, NC
$34,560 (2019) → $46,520 (2025)
Greenville, NC
$30,720 (2019) → $44,650 (2025)
View Full Salary Data
Charlotte, NC
Greenville, NC
Frequently Asked Questions
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Written by Emma Chen, CMA
Career Analyst
Emma has over 8 years of experience as a medical assistant. She has worked in both outpatient clinics and hospitals. Her expertise includes patient care and administrative support.
Methodology & Data Source
All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 4.97% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.
Data Sources & Methodology
Source: BLS, OEWS , released .
Compiled and verified by Emma Chen, CMA, a licensed medical assistant with 10+ years of clinical experience. · View source data at BLS.gov