Irvine vs Los Angeles: Medical Assistant Salary (2026)
Compare medical assistant salaries between Irvine, CA and Los Angeles, CA. All figures are 2026 estimates projected from BLS 2025 data.
Side-by-Side Comparison
| Metric | Irvine, CA | Los Angeles, CA |
|---|---|---|
| Median Salary | $53,888▲ | $50,134 |
| Hourly Rate | $25.91▲ | $24.10 |
| Entry Level (P10) | $41,647▲ | $41,106 |
| 25th Percentile | $44,933 | $48,108▲ |
| 75th Percentile | $61,067 | $62,573▲ |
| Top Earner (P90) | $73,753 | $77,615▲ |
| Total Employed | 72 | 39,770▲ |
Verdict
Irvine and Los Angeles are closely matched on overall medical assistant compensation, each winning on different metrics.
The salary gap between Irvine and Los Angeles is $3,754 (7.49%). Irvine's median is +12.36% compared to the US national median of $47,961.
Salary Range Comparison
The full salary range (10th to 90th percentile) in Irvine spans $32,106,Los Angeles spans $36,509. Los Angeles has a wider pay range, suggesting more variation in pay between entry-level and experienced medical assistants.
Cost-of-Living Adjusted Comparison
After cost-of-living adjustment, Irvine ($47,646 effective) pays 7.93% more than Los Angeles ($44,145 effective).
Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.
Which City Is Right for You?
Choose Irvine if…
- ✓Higher median salary ($53,888/year)
- ✓Better purchasing power (CoL-adjusted: $47,646)
- ✓You prefer the California area and lifestyle
Choose Los Angeles if…
- ✓Better top-earner potential ($77,615)
- ✓Larger job market (39,770 employed)
- ✓You prefer the California area and lifestyle
Historical Salary Growth Comparison
Based on BLS OEWS metropolitan area data, medical assistant salaries in Irvine grew -16.0% from 2024 to 2025, compared to 31.7% growth in Los Angeles over the same period.
Irvine, CA
$61,093 (2024) → $51,337 (2025)
Los Angeles, CA
$36,260 (2019) → $47,760 (2025)
View Full Salary Data
Irvine, CA
Los Angeles, CA
Frequently Asked Questions
Which city pays medical assistants more: Irvine or Los Angeles?
What is the hourly rate difference between Irvine and Los Angeles?
Should I relocate from Irvine to Los Angeles as a medical assistant?
What do entry-level medical assistants earn in Irvine vs Los Angeles?
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Written by Emma Chen, CMA
Career Analyst
Emma has over 8 years of experience as a medical assistant. She has worked in both outpatient clinics and hospitals. Her expertise includes patient care and administrative support.
Methodology & Data Source
All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 4.97% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.
Data Sources & Methodology
Source: BLS, OEWS , released .
Compiled and verified by Emma Chen, CMA, a licensed medical assistant with 10+ years of clinical experience. · View source data at BLS.gov