Medical Assistant Salary in Sioux Falls, SD: $45,935 (2026)
Quick Answer:A full-time medical assistant in Sioux Falls, SD earns a median $45,935/year (≈ $22.09/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 31-9092). Once you factor in Sioux Falls's price level (9% below national, BEA RPP 90.6), that paycheck buys what $50,684 would nationally. Nominal pay sits 3.2% above the South Dakota state average.
Official BLS data · View source
In Sioux Falls, South Dakota, medical assistants can anticipate a median annual salary of $45,935 in 2026, reflecting a slight decrease when compared to the national median of $47,961. The salary range for this role varies significantly, with entry-level positions starting at around $38,524 and those at the higher end earning up to $52,002 annually. This information is derived from official BLS OEWS surveys and highlights the regional pay differentials. Notably, medical assistants working in specialty practices such as dermatology and orthopedics typically receive compensation that is significantly higher than their counterparts in primary care, indicating a preference for specialized skills in Sioux Falls's healthcare market.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $38,524 | $18.52 |
| Lower Range (P25) | $40,287 | $19.37 |
| Median (P50)(typical) | $45,935 | $22.09 |
| Upper Range (P75) | $49,021 | $23.57 |
| Top Earners (P90) | $52,002 | $25.00 |
Median Salary Position
4.22% below the national average
2026 Salary Percentile Distribution in Sioux Falls
In Sioux Falls, SD, the medical assistant salary spread from the 10th to 90th percentile is $13,478 (2026 est.). At $45,935, the local median is 4.22% below the national median of $47,961.
Salary Calculator
At 40 hours/week in Sioux Falls: You'd be above the median
How Sioux Falls Medical Assistant Pay Compares
Sioux Falls median: $45,935/year (2026)
| Compared To | Median Salary | Sioux Falls Pays |
|---|---|---|
| South Dakota Average | $44,511 | +3.20% more |
| National Average | $47,961 | -4.22% less |
Medical Assistants in Sioux Falls, SD earn a median of $45,935 per year (2026 est.), which is 4.22% lower than the national median of $47,961 and 3.20% above the South Dakota state average of $44,511.
Cost-of-Living Adjusted Salary
Sioux Falls has a cost of living 9.37% below the national average, meaning your salary goes further here.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
Sioux Falls, SD has a cost-of-living index of 90.631 (below the national average of 100). A medical assistant earning $45,935 nominally has purchasing power equivalent to $50,684 in an average-cost city — an effective 10.34% boost.
Compare Purchasing Power
Select a city to see how your salary compares after cost of living
Select a city above to compare purchasing power
2019 BLS Actual
$29,510
2025 BLS Actual
$43,760
2026 Current Est.
$45,935
2019–2027 Growth
+63.4%
Salary Trajectory for Medical Assistants in Sioux Falls (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 4.97% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $29,510 | Actual |
| 2020 | $30,670 | Actual |
| 2021 | $30,540 | Actual |
| 2022 | $37,600 | Actual |
| 2023 | $35,770 | Actual |
| 2024 | $40,560 | Actual |
| 2025 | $43,760 | Actual |
| 2026(current) | $45,935 | Estimated |
| 2027 | $48,218 | Projected |
Based on 7 years of BLS OEWS data for the Sioux Falls metropolitan area, the median medical assistant salary grew 48.3% from $29,510 (2019) to $43,760 (2025). At a 4.97% compound annual growth rate, salaries are projected to reach $48,218 by 2027 — a total increase of $18,708 (63.40%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Sioux Falls metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 4.97% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $38,524 – $40,287 |
| 3-5 years (Mid Career) | $40,287 – $45,935 |
| 5+ years (Experienced) | $45,935 – $49,021 |
| 10+ years (Top Earner) | $49,021 – $52,002 |
MA, CMA salary ranges estimated from BLS percentile data. Individual medical assistant compensation varies by employer, certifications, and specialization.
Medical Assistant Job Market in Sioux Falls
The job market for medical assistants in Sioux Falls is robust, with 620 professionals currently employed in the area. Residents benefit from a cost-of-living index of 90.631, which suggests that salaries stretch further than in higher-cost areas, enhancing purchasing power. Among local employers, specialty clinics, particularly cardiology and dermatology, tend to offer the highest compensation, primarily due to the increased demand for skilled medical support staff. Several factors contribute to disparities in pay, including the prevalence of bilingual capabilities, specialized certifications, and additional responsibilities such as lead positions. For those looking to enhance their earning potential in Sioux Falls, pursuing certifications from recognized bodies like AAMA or AMT, and gaining experience in high-demand areas such as urgent care or specialty practices can prove beneficial.
More salary data for Sioux Falls, SD:
Frequently Asked Questions
How much do medical assistants make in Sioux Falls, SD in 2026?
Is Sioux Falls, SD a good place to work as a medical assistant?
Can medical assistants make $100K in Sioux Falls?
What is the cost-of-living adjusted medical assistant salary in Sioux Falls?
How much does a medical assistant make per hour in Sioux Falls?
Related Pages
Compare Salaries
Career Resources
Nearby Cities in South Dakota
Written by Emma Chen, CMA
Career Analyst
Emma has over 8 years of experience as a medical assistant. She has worked in both outpatient clinics and hospitals. Her expertise includes patient care and administrative support.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $43,760 for medical assistantsin the Sioux Falls metropolitan area. A 4.97% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Source: BLS, OEWS, 7-year dataset (–). Per-city data from annual BLS metropolitan area surveys.
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 4.97%, derived from historical BLS wage trends for medical assistants (SOC 31-9092).
Compiled and verified by Emma Chen, CMA, a licensed medical assistant with 10+ years of clinical experience. · View source data at BLS.gov